2-Bromo-5-chlorobenzoic acid → 5-chloro-2-(2H-1,2,3-triazol-2-yl)benzoic acid

HRID 61083Notes

Reaction equation

HRID 61083 reaction equation
C[C:2]1[CH:3]=[CH:4][C:5]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].BrC1C=CC([Cl:26])=CC=1C(O)=O>>[Cl:26][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 890272-Bromo-5-chlorobenzoic acidHCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Product 1

HCID 670867345-chloro-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Procedure

The title compound was prepared following the same general protocol as described for 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A11 using 2-bromo-5-chlorobenzoic acid. MS (ESI) 224 (M+H).

Sources & evidence

ORD record
ord-98f87c8439374cf5821dda98150c748e
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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