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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61085Generated: October 25, 2026

2-Chloro-5-(trifluoromethyl)pyrimidine → HCID 117727673, compound

https://huagongshe.com/reaction/61085

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyrimidineHCID 13317019—
Reactant((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-chloro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanoneHCID 117727775—
ProductHCID 117727673HCID 117727673—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example A45 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-chloro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. MS (ESI) 480 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-c759217863b84d3d97244c1fed12ecc0
Source noteuspto-grants-2016_09