HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4,5,6,7-Tetrahydrofuro[2,3-c]pyridine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 4,7-dihydrofuro[2,3-c]pyridine-6(5H)-carboxylate | HCID 11424602 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4,5,6,7-Tetrahydrofuro[2,3-c]pyridine hydrochloride | HCID 19599907 | — |
Reaction Steps
To a solution of 5.324 g (23.85 mmol) of 6-tert-butoxycarbonyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine in 100 ml of methanol, 5 ml of concentrated hydrochloric acid was added, followed by stirring at room temperature for 1 hour. The solvent was distilled off under reduced pressure to yield the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998433 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-f77f909810404d96a4ab11341ffd9def |
| Source note | uspto-grants-1999_12 |