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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 611121Generated: October 25, 2026

Hydrochloric Acid → 2-(4-benzyloxy-3-methoxyphenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)ethan-1-one hydrochloride

https://huagongshe.com/reaction/611121

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-(4-Benzyloxy-3-methoxy-phenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)ethane-1-oneHCID 19599997—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
Product2-(4-benzyloxy-3-methoxyphenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)ethan-1-one hydrochlorideHCID 19600097—

Reaction Steps

2-(4-Benzyloxy-3-methoxy-phenyl)-1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)ethane-1-one 0.197 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05998433
Source datasetuspto-grants-1999_12
ORD IDord-048197d912ba4961b5f8f77ed2e3483e
Source noteuspto-grants-1999_12