HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Acid → 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Acid | HCID 1017 | — |
| Reactant | 4-(3-Aminopropylthio)pyridine | HCID 15227695 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine | HCID 19079108 | 92.3% |
Reaction Steps
A solution of 340 mg (2.02 mmol) of 4-(3-aminopropylthio)pyridine and 738 mg (4.98 mmol) of anhydrous phthalic acid in 5 ml of methylene chloride was stirred at room temperature for 30 minutes. The resulting crystals were filtered and dried to obtain 590 mg of the desired compound (92.3%, colorless powder), mp: 151.0°-153.3° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05246948 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-c868b3c19e0d4a2d82a6e4b451c62930 |
| Source note | uspto-grants-1993_09 |