Di-tert-butyl dicarbonate → Di-tert-butyl dicarbonate

Participants

Reaction Steps

To a solution of the above crude N-[3-(3-furyl)propyl]-6-phenylhexylamine in 100 ml of dichloromethane, 2.49 g (11.4 mmol) of di-tert-butyl dicarbonate was added, followed by stirring at room temperature for 2 hours. The solvent was distilled off under reduced pressure. The resulting crude product was purified by silica gel column chromatography (hexane/ethyl acetate=9/1) to yield N-(tert-butoxycarbonyl)-N-[3-(3-furyl)propyl]-6-phenylhexylamine as a mixture with di-tert-butyl dicarbonate.

Provenance & Evidence