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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 611242Generated: November 2, 2026

HCID 19600120, compound → Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

https://huagongshe.com/reaction/611242

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19600120HCID 19600120—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductMethyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylateHCID 19600098—

Reaction Steps

A solution of 0.285 g (1.050 mmol) of methyl 6-benzyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate in 30 ml of methanol was hydrogenated at room temperature at atmospheric pressure over 0.2 g of 10% palladium-carbon (50% wet) overnight. After the catalyst was filtered off, the filtrate was evaporated under reduced pressure to yield the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05998433
Source datasetuspto-grants-1999_12
ORD IDord-bef794c704fe44a4bed37bbfb8a46dbd
Source noteuspto-grants-1999_12