2-Fluoro-5-(trifluoromethyl)pyridine → ((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Fluoro-5-(trifluoromethyl)pyridine	HCID 5463754	—
Edukt	((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanone	HCID 117727833	—
Produkt	((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanone	HCID 117728061	—

Reaktionsschritte

The title compound was prepared following the same general protocol as described for Example A1, using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanone and 2-fluoro-5-trifluoromethylpyridine. ESI-MS (m/z): 470 [M+1]+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09440982B2
Quelldatensatz	uspto-grants-2016_09
ORD ID	ord-e1c0f99c6e9b44baa07f7488100ae0ae
Quellennotiz	uspto-grants-2016_09