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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61130Generated: October 25, 2026

2-Chloro-5-(trifluoromethyl)pyrimidine → HCID 117728235, compound

https://huagongshe.com/reaction/61130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyrimidineHCID 13317019—
Reactant((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanoneHCID 117727833—
ProductHCID 117728235HCID 117728235—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example A1, using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyridazin-3-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 471 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-1c34187ba93a4799a45edd4bcb7c2f31
Source noteuspto-grants-2016_09