HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (E)-N,N-dimethyl-[6-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (E)-N,N-dimethyl-[6-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine | HCID 19599936 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (E)-N,N-dimethyl-[6-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride | HCID 19599935 | — |
Reaction Steps
(E)-N,N-Dimethyl-[6-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.509 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05998433 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-7c9bd9e4e15543b899359f032a823968 |
| Source note | uspto-grants-1999_12 |