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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61139Generated: October 29, 2026

2-Chlorobenzoxazole → ((2S,3R)-2-((Benzo[d]oxazol-2-ylamino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone

https://huagongshe.com/reaction/61139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzoxazoleHCID 11986—
Reactant((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanoneHCID 117727676—
Product((2S,3R)-2-((Benzo[d]oxazol-2-ylamino)methyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanoneHCID 117727950—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example A2 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone and 2-chlorobenzoxazole. MS (ESI) 442 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-4191c5a1c680476d86ebd019b6dfab51
Source noteuspto-grants-2016_09