Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61143Generated: October 31, 2026

2-Chloro-5-(trifluoromethyl)pyrimidine → HCID 117727892, compound

https://huagongshe.com/reaction/61143

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyrimidineHCID 13317019—
Reactant((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanoneHCID 117727786—
ProductHCID 117727892HCID 117727892—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example A45 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. MS (ESI) 464 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-1613c43efeb14a14a83f1ce9c89e8c65
Source noteuspto-grants-2016_09