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HRID61152

反应详情

EQUATION

反应方程式

HRID 61152 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1cnc(Cl)nc1
HCID13317019

2-Chloro-5-(trifluoromethyl)pyrimidine

C5H2ClF3N2

结构：Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1
HCID117727676

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc(C(F)(F)F)cn2)c1
HCID117728264

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described for Example A45 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. MS (ESI) 471 (M+H). 1H NMR (500 MHz, CD3OD) δ 8.90-6.60 (m, 8H), 5.15-3.00 (m, 5H), 2.45-0.65 (m, 11H).