反应详情

5-(4-Amino-3-methoxyphenyl)-4-chloro-7-cyclopentylpyrrolo[2,3-d]pyrimidine (0.50 g, prepared in a similar manner to Example 32) was reacted with benzenesulphonyl chloride (0.31 g) in pyridine (5 ml) and dichloromethane (1 ml) at 0° C. and the product obtained after work-up was reacted with ammonia in a similar manner to Example 32 to give N-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methoxyphenyl]benzenesulphonamide, m.p. 113-115° C. The structure was confirmed by 1H nmr and mass spectra.

1. customthe product obtained after work-up