HCID 86754943, compound → HCID 178473058, compound

HRID 611606Notes

Reaction equation

HRID 611606 reaction equation
[NH:1]([C:5]1[S:6][C:7]([C:10]([OH:12])=O)=[CH:8][N:9]=1)[C:2]([NH2:4])=[NH:3].Cl.[NH:14]1[CH2:19][CH2:18][CH2:17][CH:16]([CH2:20][O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:15]1>>[NH:1]([C:5]1[S:6][C:7]([C:10]([N:14]2[CH2:19][CH2:18][CH2:17][CH:16]([CH2:20][O:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:15]2)=[O:12])=[CH:8][N:9]=1)[C:2]([NH2:4])=[NH:3]

Participants

3

Reactant 2

HCID 86754943HCID 86754943, compoundHCID 178512680HCID 178512680, compound

Product 1

HCID 178473058HCID 178473058, compound

Procedure

In the same manner as described in Example 4, from 2-guanidino-thiazole-5-carboxylic acid and ethyl (RS)-(piperidin-3-ylmethoxy)-acetate hydrochloride there is obtained ethyl (RS)-[1-(2-guanidino-thiazole-5-carbonyl)-piperidin-3-ylmethoxy]-acetate, m.p. 156° C., MS: 370 (M+H)+.

Sources & evidence

ORD record
ord-96db7171919649258ed78c2be7ef4e36
Source dataset
uspto-grants-1999_12
Patent number
US06001855

Reaction notes

Loading…