HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | HCID 178418303 | HCID 178418303 | — |
| Product | 2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one | HCID 23287902 | 87.6% |
Reaction Steps
Using the procedure of Example 20, 2.0 g (6.22 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid benzylamide (from Preparation 42) was reacted with 1.74 g (6.8 mmol) of iodine to give 1.74 g of the title compound after crystallization from isopropanol, mp 166-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06001863 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-87e678f999894fe58eb8a6b3818292c8 |
| Source note | uspto-grants-1999_12 |