HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 6-Phenyl-2-(2-pyridin-2-yl-ethyl)-isothiazolo[5,4-d]pyrimidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | HCID 178418325 | HCID 178418325 | — |
| Product | 6-Phenyl-2-(2-pyridin-2-yl-ethyl)-isothiazolo[5,4-d]pyrimidin-3-one | HCID 23287886 | 91.3% |
Reaction Steps
Using the procedure of Example 20, 14.0 g (41.6 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-pyridin-2-yl-ethyl)-amide were treated with 10.6 g (41.7 mmol) of iodine to give 12.7 g of the title compound after recrystallization from ethanol, mp 132-133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06001863 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-50c7bf13d1d440858a03aaae04b5d7e6 |
| Source note | uspto-grants-1999_12 |