Trimethyl orthoformate → HCID 19598016, compound

HRID 611691Notes

Reaction equation

HRID 611691 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1C=O.[CH:13]([O:18][CH3:19])([O:16][CH3:17])OC>CO>[OH:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:13]([O:16][CH3:17])[O:18][CH3:19]

Participants

4

Reactant 2

HCID 9005Trimethyl orthoformateHCID 668085-Nitrosalicylaldehyde

Product 1

HCID 19598016HCID 19598016, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-Hydroxy-5-nitrobenzaldehyde (3.34 g) was dissolved in methanol (30 ml). Trimethyl orthoformate (20 ml) and then Dowex 50W×8 (H+ form)(generally 2 ml) were added to this solution. The mixture was stirred for 30 min. at room temperature. The resin was removed from the reaction mixture by passing the mixture through an alumina. The filtrate was evaporated to give the title compound (4.0 g) having the following physical data.

Workup

  1. customThe resin was removed from the reaction mixture
  2. customThe filtrate was evaporated

Sources & evidence

ORD record
ord-d1b160a14cca469cbc8b12fb400ef927
Source dataset
uspto-grants-1999_12
Patent number
US06001877

Reaction notes

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