Chlorotrimethylsilane → HCID 19598186, compound

HRID 611730Notes

Reaction equation

HRID 611730 reaction equation
[C:1]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)(=[O:4])[CH:2]=[CH2:3].[CH3:14][Si:15]([CH3:18])([CH3:17])Cl>C(C(C)=O)C(C)C>[C:1]([O:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][Si:15]([CH3:18])([CH3:17])[CH3:14])=[CH:11][CH:12]=1)(=[O:4])[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 22123752HCID 22123752, compound

Product 1

HCID 19598186HCID 19598186, compoundYield 59.1%

Reagents, catalysts & solvents 1

HCID 7909Methyl Isobutyl KetoneSolvent

Conditions

Temperature
-5 °C

Procedure

1500 g of methyl isobutyl ketone and 100 g of 4-hydroxybenzyl acrylate were charged into a separable flask of the same type as used in Reference Example 1, and cooled to -5° C. while replacing the flask inside gas with a nitrogen gas, and then 67 g of trimethylchlorosilane was dropwise added thereto over one hour, and then stirring was continued for 2 hours. After completion of the reaction, the reaction mixture was washed with water and methyl isobutyl ketone was distilled off, whereby 83 g of p-trimethylsilyloxybenzyl acrylate of the following chemical formula was obtained (yield: 59%): ##STR13##

Workup

  1. waitwas continued for 2 hours
  2. customAfter completion of the reaction
  3. washthe reaction mixture was washed with water and methyl isobutyl ketone
  4. distillationwas distilled off

Sources & evidence

ORD record
ord-cad1fe71f81b4a6eab5f5a24949e5ec4
Source dataset
uspto-grants-1999_12
Patent number
US06001932

Reaction notes

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