HRID61191

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13317019

2-Chloro-5-(trifluoromethyl)pyrimidine

C5H2ClF3N2

结构：C[C@@H]1CCCN(C(=O)c2ccc(F)cc2-c2ncccn2)[C@@H]1CN

HCID117727804

未命名化合物

PRODUCTS

生成物

结构：C[C@@H]1CCCN(C(=O)c2ccc(F)cc2-c2ncccn2)[C@@H]1CNc1ncc(C(F)(F)F)cn1

HCID117728295

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described for Example A1 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(4-fluoro-2-(pyrimidin-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 475 [M+1]+. 1H NMR (300 MHz, DMSO-d6) δ 9.00-6.70 (m, 9H), 4.95-2.75 (m, 5H), 2.00-0.65 (m, 8H).