HuagongsheHuagongshe Chemistry Print Report · For research reference only
Decyl chloroformate → N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Decyl chloroformate | HCID 108727 | — |
| Reactant | N-[2-[4-(6-fluoro1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide | HCID 18467209 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride | HCID 18467279 | — |
Reaction Steps
A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06001834 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-55eb0ae9a081402aaf30738b594dcd43 |
| Source note | uspto-grants-1999_12 |