HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → 6,7-Dimethoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Reactant | 2-Cyano-3-(3,4-dimethoxyphenylamino)acrylic acid ethyl ester | HCID 69162570 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 6,7-Dimethoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile | HCID 11183814 | — |
Reaction Steps
A mixture of 40 g of ethyl 2-cyano-3-(3,4-dimethoxyphenylamino)acrylate and 1.2 L of Dowtherm® A was refluxed for 10 h, cooled, and diluted with hexane. The resulting solid was filtered, washed with hexane followed by dichloromethane, and dried; mp 330-350° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06002008 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-f0dc3f8cbd6246699c29bb7beec40f17 |
| Source note | uspto-grants-1999_12 |