HRID61206

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13317019

2-Chloro-5-(trifluoromethyl)pyrimidine

C5H2ClF3N2

结构：C[C@@H]1CCCN(C(=O)c2cc(F)c(F)cc2-c2ncccn2)[C@@H]1CN

HCID117727894

未命名化合物

PRODUCTS

生成物

结构：C[C@@H]1CCCN(C(=O)c2cc(F)c(F)cc2-c2ncccn2)[C@@H]1CNc1ncc(C(F)(F)F)cn1

HCID117728335

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described for Example A1 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(4,5-difluoro-2-(pyrimidin-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 493 [M+1]+. 1H NMR (500 MHz, DMSO-d6) δ 8.95-6.75 (m, 8H), 4.95-2.85 (m, 5H), 1.95-0.65 (m, 8H).