4,5-Difluoro-2-iodobenzoic acid → HCID 67116235, compound

HRID 61208Notes

Reaction equation

HRID 61208 reaction equation
CC1C=CC([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)=C(C=1)C(O)=O.[F:16][C:17]1[C:25]([F:26])=[CH:24][C:20]([C:21]([OH:23])=[O:22])=[C:19](I)[CH:18]=1.N1C=CN=N1>>[F:16][C:17]1[C:25]([F:26])=[CH:24][C:20]([C:21]([OH:23])=[O:22])=[C:19]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[CH:18]=1

Participants

4

Reactant 3

HCID 149974724,5-Difluoro-2-iodobenzoic acidHCID 532601655-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 178418936HCID 178418936, compound

Product 1

HCID 67116235HCID 67116235, compound

Procedure

The title compound was prepared following the same general protocol as described for 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A11 using 4,5-difluoro-2-iodobenzoic acid and 1,2,3-triazole. ESI-MS (m/z): 226 [M+1]+.

Sources & evidence

ORD record
ord-2e0cfb3ef99047f1b578c1e28ff40538
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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