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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 612168Generated: October 25, 2026

4-Chloro-6,7-dimethoxy-quinoline-3-carbonitrile → 4-[3-Chloro-4-(phenylthio)phenylamino]-6,7-dimethoxy-3-quinolinecarbonitrile

https://huagongshe.com/reaction/612168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6,7-dimethoxy-quinoline-3-carbonitrileHCID 10586676—
Reactant3-Chloro-4-(phenylsulfanyl)anilineHCID 23438083—
Product4-[3-Chloro-4-(phenylthio)phenylamino]-6,7-dimethoxy-3-quinolinecarbonitrileHCID 22466665—

Reaction Steps

In the manner of Example 105 reaction of 4-chloro-6,7-dimethoxy-3-quinolinecarbonitrile with 3-chloro-4-(phenylthio)aniline gave the title compound as a tan solid, mp 124-130° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06002008
Source datasetuspto-grants-1999_12
ORD IDord-8c60fab84b3246c38971de26c4b4e770
Source noteuspto-grants-1999_12