3'-Aminoacetophenone → HCID 22466703, compound

HRID 612170Notes

Reaction equation

HRID 612170 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:15][CH2:16][CH3:17])=[C:9]([O:12][CH2:13][CH3:14])[CH:10]=2)[N:5]=[CH:4][C:3]=1[C:18]#[N:19].[CH3:20][C:21]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([NH2:29])[CH:24]=1)=[O:22]>>[C:21]([C:23]1[CH:24]=[C:25]([NH:29][C:2]2[C:11]3[C:6](=[CH:7][C:8]([O:15][CH2:16][CH3:17])=[C:9]([O:12][CH2:13][CH3:14])[CH:10]=3)[N:5]=[CH:4][C:3]=2[C:18]#[N:19])[CH:26]=[CH:27][CH:28]=1)(=[O:22])[CH3:20]

Participants

3

Reactant 2

HCID 74173'-AminoacetophenoneHCID 107788724-Chloro-6,7-diethoxyquinoline-3-carbonitrile

Product 1

HCID 22466703HCID 22466703, compound

Procedure

In the manner of Example 105 reaction of 4-chloro-6,7-diethoxy-3-quinolinecarbonitrile with 3-aminoacetophenone gave the tide compound as an off-white solid, mp 191-194° C.

Sources & evidence

ORD record
ord-5158958c55c741ee991ecb394d7152eb
Source dataset
uspto-grants-1999_12
Patent number
US06002008

Reaction notes

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