huagongshe.com
HRID61240

反应详情

EQUATION

反应方程式

HRID 61240 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1cnc(Cl)nc1
HCID13317019

2-Chloro-5-(trifluoromethyl)pyrimidine

C5H2ClF3N2

结构：Cc1ccc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-n2nccn2)c1
HCID117727665

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc(C(F)(F)F)cn2)c(-n2nccn2)c1
HCID117727878

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described for Example A89 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(4-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone and 2-chloro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 460.2 [M+1]+. 1H NMR (300 MHz, DMSO-d6) δ 8.45-6.65 (m, 8H), 4.90-2.70 (m, 5H), 2.45-0.60 (m, 11H).