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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61243Generated: October 25, 2026

2-Fluoro-5-(trifluoromethyl)pyridine → HCID 117727861, compound

https://huagongshe.com/reaction/61243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)pyridineHCID 5463754—
Reactant2-Iodo-6-methylbenzoic acidHCID 9856531—
ReactantHCID 117728173HCID 117728173—
ProductHCID 117727861HCID 117727861—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example A230 using 2-iodo-6-methylbenzoic acid to make ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(2-methyl-6-(pyrimidin-2-yl)phenyl)methanone and 2-fluoro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 470 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-c2bed0fb38f7421fae54e6d1dbc6f1cd
Source noteuspto-grants-2016_09