Triethylamine → HCID 10130538, compound

Participants

Reaction Steps

Triethylamine (10.5 ml) was added to a solution of alpha, alpha'-dibromo-o-xylene (10 g) and 2-hydrazinopyridine (4.1 g) in dimethylformamide. The mixture was stirred, under nitrogen, at ambient temperature for about 20 mins and diluted with water and ethyl acetate. The organic layer was separated, washed with water and brine, dried over anhydrous sodium sulfate, filtered, and the filtrate was concentrated. Trituration of the residue with ethyl acetate gave 3.8 g (48%) of product. Recrystallization of the product from ethyl acetate afforded the analytical sample, mp 130-131° C.

Provenance & Evidence