HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 70106633, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 4-Hydrazinylpyridine hydrochloride | HCID 22320258 | — |
| Reactant | HCID 54239204 | HCID 54239204 | — |
| Product | HCID 70106633 | HCID 70106633 | 72.2% |
Reaction Steps
A mixture of 5-benzyloxy-2-bromo-4-methoxy-3-(2-methoxyvinyl)benzene (42.1 g), 4-hydrazinopyridine hydrochloride (19.0 g), p-toluenesulfonic acid (0.23 g) and ethanol (350 ml) was heated under reflux overnight, with stirring. The reaction mixture was cooled and filtered. Recrystallization of the precipitate from methanol yielded 40.2 g, (72.2%) of product, mp 232-233° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06004977 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-df82681ab1774668a1d4365f6d5b543f |
| Source note | uspto-grants-1999_12 |