Methanol → HCID 19595213, compound

Participants

Reaction Steps

To a solution of 2,3-dihydro-4-chloro-7-methoxy-N-(4-pyridinyl)-1H-isoindol-2-amine hydrochloride (1.12 g) in dichloromethane (10 mL) was added boron tribromide (1.0 mL ) at 0° C. The solution was warmed to ambient temperature and stirred for 3 days. Methanol was added, and the mixture was filtered to give 1.2 g (79%) of product, mp>240° C. (decomp).

Provenance & Evidence