HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 23283703, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | HCID 23283702 | HCID 23283702 | — |
| Product | HCID 23283703 | HCID 23283703 | — |
Reaction Steps
145 mg of N-[2-(5-methoxyindol-3-yl)ethyl]glutarimide are dissolved in DMSO (30 μl) in a round-bottomed flask and concentrated HCl (72 μl) is added with stirring. The mixture is stirred overnight at room temperature. The crude product is neutralized with NH3 and then extracted with EtOAc. After separation on a silica plate, N-[2-(5-methoxy-2-oxo-2,3-dihydroindol-3-yl)ethyl]-glutarimide is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06004991 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-04bb05f90d0e4b4bb7ac766b843e09e1 |
| Source note | uspto-grants-1999_12 |