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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61256Generated: October 31, 2026

2-Chloro-5-(trifluoromethyl)pyridine → HCID 117728221, compound

https://huagongshe.com/reaction/61256

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
Reactant2-(((2S,3R)-3-Methylpiperidin-2-yl)methyl)isoindoline-1,3-dioneHCID 117727630—
Reactant3,4-difluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 117727909—
ProductHCID 117728221HCID 117728221—

Reaction Steps

The title compound was prepared following the same general protocol as described in Example A318, using 3,4-difluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid, 2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione and 2-chloro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 481 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-bc507b340e1f4d528c251b0c75de3deb
Source noteuspto-grants-2016_09