3,5-Difluoro-2-iodobenzoic acid → 3,5-difluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid

HRID 61257Notes

Reaction equation

HRID 61257 reaction equation
[F:1][C:2]1[C:3](I)=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5]([OH:7])=[O:6].[NH:13]1[CH:17]=[CH:16][N:15]=[N:14]1>>[F:1][C:2]1[C:3]([N:14]2[N:15]=[CH:16][CH:17]=[N:13]2)=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5]([OH:7])=[O:6]

Participants

3

Reactant 2

HCID 898164633,5-Difluoro-2-iodobenzoic acidHCID 178418936HCID 178418936, compound

Product 1

HCID 1177279223,5-difluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Procedure

The title compound was prepared using the methods described herein, using 3,5-difluoro-2-iodobenzoic acid and 1,2,3-triazole. ESI-MS (m/z): 226 [M+1]+.

Sources & evidence

ORD record
ord-ed5c8015ecbb41d49b7ecafbed50dfde
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

Loading…