反应详情

Dimethyl 4-nitrophthalate was reacted in DMF with 3-hydroxypyridine sodium salt in analogy to a process known from the literature (J. Org. Chem. Vol. 42, No. 21, 1977, 3419-3425) to give dimethyl 4-(3-pyridyloxy)phthalate. After standard working up and chromatography using hexane/EA, the diester was isolated as a yellowish oil.