HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-(diethylamine)ethane hydrochloride → HCID 9800193, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-(diethylamine)ethane hydrochloride | HCID 13363 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 19594704 | HCID 19594704 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | HCID 9800193 | HCID 9800193 | 47.1% |
Reaction Steps
In a manner analagous to Example 9B, react 5-hydroxy-2-propoxy-4-methoxy-fluoren-9-one (1.75 g, 6.1) in 5 mL methanol and 100 mL chlorobenzene with 2-chloroethyldiethyl amine hydrochloride (4.4 g, 25 mmole) and sodium methoxide (0.51 g, 9.5 mmole) and reflux for 2 hours then continue as in Example 9B to give 1.1 g. of the title compound (2.9 mmole, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06004959 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-5ae60d393d8f4f01b9408b0967c3ef20 |
| Source note | uspto-grants-1999_12 |