1-(2-Chloroethyl)pyrrolidine → HCID 70190988, compound

Participants

Reaction Steps

5-Hydroxy-4-methoxy-2-propyloxy-fluoren-9-one (0.83 g, 2.9 mmole) and 2-chloroethylpyrrolidine and sodium methoxide (0.20 g, 3.5 mmole) are reacted as described in Example 9B to give a red powder, which when recrystallized from 2-butanone gives the title compound. (0.222 g, 18%). m.p. 147°-149° C. Analysis calculated for C23H27NO4.HCl; C, 66.10, H, 6.75, N, 3.35. Found: C, 65.82, H, 6.65; N, 3.09. The compound has the following structure: ##STR50##

Provenance & Evidence