2-Bromophenyl isocyanate → N-(2-hydroxy 4-trifluoromethylphenyl) N'-(2-bromophenyl)urea

Participants

Reaction Steps

The urea was prepared from 2-hydroxy 4-trifluoromethyl aniline(example 7a, 0.171 g, 1 mmol) and 2-bromo phenyl isocyanate (1 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compounds (0.25 g, 54%). EI-MS m/z 375 (M+H)+

Provenance & Evidence