Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Phenoxybenzoic acid | HCID 75237 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | 2-Amino-5-Nitrophenol | HCID 4984721 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 9950992 | HCID 9950992 | — |
Reaction Steps
The urea was synthesized by the treatment of 2-phenoxyphenyl carboxylic acid (2 mmol,) with diphenyl phosphoryl azide (0.475 mL) and triethyl amine (0.14 mL) in DMF at 80° C. after 24 hours the 2-amino 5-nitro phenol (1 equiv.) was added. The reaction was heated for 24 hours at 80° C. The reaction product was oiled out with hexane. The residue was dissolved in methanol and the solid was precipitated out with water. (180) mg. 24%) EI-MS m/z 364 (M-H)-
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06005008 |
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| Source dataset | uspto-grants-1999_12 |
|---|
| ORD ID | ord-c07fcf9717b44d5dbb9083a716dc5954 |
|---|
| Source note | uspto-grants-1999_12 |
|---|
