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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 612665Generated: October 30, 2026

(1,1'-Biphenyl)-3-ol, 4-nitro- → 2-Amino-5-phenylphenol

https://huagongshe.com/reaction/612665

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-ol, 4-nitro-HCID 87437—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-Amino-5-phenylphenolHCID 20376—

Reaction Steps

A solution of 2-nitro 5-phenyl phenol (1.2 g, 5.5 mmol) in methanol was treated with 10% Pd/C (1.2 g). The reaction mixture was flushed with hydrogen and allowed to stir overnight. The reaction mixture was filtered through celite and the filtrate was concentrated in vacuo to afford desired (0.01 g, 98%) EI-MS m/z 186(M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06005008
Source datasetuspto-grants-1999_12
ORD IDord-1366e9b428604acb859691ec2713be3c
Source noteuspto-grants-1999_12