O-Phenylenediamine → N-(2-Aminophenyl)-3-methylbenzenesulfonamide

HRID 612674Notes

Reaction equation

HRID 612674 reaction equation
[C:1]1([CH3:11])[CH:6]=[CH:5][CH:4]=[C:3]([S:7](Cl)(=[O:9])=[O:8])[CH:2]=1.[C:12]1([NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18]>>[C:1]1([CH3:11])[CH:6]=[CH:5][CH:4]=[C:3]([S:7]([NH:18][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[NH2:19])(=[O:9])=[O:8])[CH:2]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 27345953-Methylbenzenesulphonyl chloride

Product 1

HCID 16773320N-(2-Aminophenyl)-3-methylbenzenesulfonamide

Procedure

The sulfonamide was synthesized from 3-tolylsulfonyl chloride (0.01 mol) and o-phenylene diamine (0.01 mol) by general Method C. It was purified by recrystallization from EtOH (0.73 g, 28%). EI-MS m/z 263 (M+H)+

Workup

  1. customIt was purified by recrystallization from EtOH (0.73 g, 28%)

Sources & evidence

ORD record
ord-04b829ce1e7d4f5ba3e0d7ce58720bb4
Source dataset
uspto-grants-1999_12
Patent number
US06005008

Reaction notes

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