O-Phenylenediamine → 2-(Benzylsulfonylamino)aniline

HRID 612677Notes

Reaction equation

HRID 612677 reaction equation
[CH2:1]([S:8](Cl)(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]1([NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18]>>[CH2:1]([S:8]([NH:18][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=1[NH2:19])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 74740Phenylmethanesulfonyl chloride

Product 1

HCID 167784432-(Benzylsulfonylamino)aniline

Procedure

The sulfonamide was synthesized from benzyl sulfonyl chloride (0.01 mol) and o-phenylene diamine (0.01 mol) by general Method C. It was purified by recrystallization from EtOH (0.87 g, 33%) EI-MS m/z 263 (M+H)+.

Workup

  1. customIt was purified by recrystallization from EtOH (0.87 g, 33%) EI-MS m/z 263 (M+H)+

Sources & evidence

ORD record
ord-75f525bf598b437d84385c8d33d78ce7
Source dataset
uspto-grants-1999_12
Patent number
US06005008

Reaction notes

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