4-Fluoro-2-iodo-3-methylbenzoic acid → 4-Fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid
Reaction equation
F[C:2]1[C:7]([C:8]([OH:10])=[O:9])=[C:6]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[C:5]([CH3:16])=[CH:4][CH:3]=1.[F:17]C1C=CC(C(O)=O)=C(I)C=1C>>[F:17][C:4]1[CH:3]=[CH:2][C:7]([C:8]([OH:10])=[O:9])=[C:6]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[C:5]=1[CH3:16]Participants
3
Procedure
The title compound was prepared following the same general protocol as described for 6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A352 using 4-fluoro-2-iodo-3-methylbenzoic acid. MS (ESI) 222 (M+H).
Sources & evidence
- ORD record
- ord-35f41cb9842649f4a1637620e13896d0
- Source dataset
- uspto-grants-2016_09
- Patent number
- US09440982B2
Reaction notes
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