O-Phenylenediamine → 2-((4-Phenoxyphenyl)sulfonylamino)aniline

Participants

Reaction Steps

The title compound was prepared according to General Method C using 4-phenoxyphenylsulfonyl chloride (969 mg, 3.6 mmol) and o-phenylenediamine (300 mg, 2.77 mmol). The reaction mixture was partitioned between water (200 ml) and toluene:methylene chloride (1:3). The organic phase collected and the methylene chloride evaporated leaving the toluene. Hexane added and the product precipitated from solution. (317 mg, 34%) EI-MS m/z 341 (M+H)+

Provenance & Evidence