6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid → HCID 117727987, compound

HRID 61276Notes

Reaction equation

HRID 61276 reaction equation
FC1C(C(O)=O)=C([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)C(C)=CC=1.[F:17][C:18]1[C:19](I)=[C:20]([CH:24]=[CH:25][C:26]=1[CH3:27])[C:21]([OH:23])=[O:22]>>[F:17][C:18]1[C:19]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)=[C:20]([CH:24]=[CH:25][C:26]=1[CH3:27])[C:21]([OH:23])=[O:22]

Participants

3

Reactant 2

HCID 1177276806-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 1177277803-Fluoro-2-iodo-4-methylbenzoic acid

Product 1

HCID 117727987HCID 117727987, compound

Procedure

The title compound was prepared following the same general protocol as described for 6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A352 using 3-fluoro-2-iodo-4-methylbenzoic acid. MS (ESI) 222 (M+H).

Sources & evidence

ORD record
ord-d0a81dc895f844faa4ec3e2f75d3b14c
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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