6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid → 4-Fluoro-5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

HRID 61280Notes

Reaction equation

HRID 61280 reaction equation
FC1C(C(O)=O)=C([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)C(C)=CC=1.[F:17][C:18]1[C:26]([CH3:27])=[CH:25][C:21]([C:22]([OH:24])=[O:23])=[C:20](I)[CH:19]=1>>[F:17][C:18]1[C:26]([CH3:27])=[CH:25][C:21]([C:22]([OH:24])=[O:23])=[C:20]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[CH:19]=1

Participants

3

Reactant 2

HCID 1177276806-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 1177277444-Fluoro-2-iodo-5-methylbenzoic acid

Product 1

HCID 1177276404-Fluoro-5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Procedure

The title compound was prepared following the same general protocol as described for 6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A352 using 4-fluoro-2-iodo-5-methylbenzoic acid. MS (ESI) 222 (M+H).

Sources & evidence

ORD record
ord-ea9e601ffd9e49b9901cf09348daff38
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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