3-Fluoro-6-iodo-2-methylbenzoic acid → 3-Fluoro-2-methyl-6-(2H-1,2,3-triazol-2-yl)benzoic acid

HRID 61284Notes

Reaction equation

HRID 61284 reaction equation
FC1C(C(O)=O)=C([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)C(C)=CC=1.[F:17][C:18]1[C:19]([CH3:28])=[C:20]([C:24](I)=[CH:25][CH:26]=1)[C:21]([OH:23])=[O:22]>>[F:17][C:18]1[C:19]([CH3:28])=[C:20]([C:24]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)=[CH:25][CH:26]=1)[C:21]([OH:23])=[O:22]

Participants

3

Reactant 2

HCID 711493863-Fluoro-6-iodo-2-methylbenzoic acidHCID 1177276806-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

Product 1

HCID 1177278493-Fluoro-2-methyl-6-(2H-1,2,3-triazol-2-yl)benzoic acid

Procedure

The title compound was prepared following the same general protocol as described for 6-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid in Example A352 using 3-fluoro-6-iodo-2-methylbenzoic acid. MS (ESI) 222 (M+H).

Sources & evidence

ORD record
ord-ee3ded4e12844ac29b87e72c14794acc
Source dataset
uspto-grants-2016_09
Patent number
US09440982B2

Reaction notes

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