tert-butyl N-(2-hydroxyethyl)carbamate → HCID 19596681, compound

HRID 612889Notes

Reaction equation

HRID 612889 reaction equation
[OH:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[CH:9][CH:8]=2)[O:4][N:3]=1.[C:19]([O:23][C:24]([NH:26][CH2:27][CH2:28]O)=[O:25])([CH3:22])([CH3:21])[CH3:20]>>[C:19]([O:23][C:24]([NH:26][CH2:27][CH2:28][O:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[CH:9][CH:8]=2)[O:4][N:3]=1)=[O:25])([CH3:22])([CH3:21])[CH3:20]

Participants

3

Reactant 2

HCID 2733206tert-butyl N-(2-hydroxyethyl)carbamateHCID 178515515HCID 178515515, compound

Product 1

HCID 19596681HCID 19596681, compoundYield 69%

Procedure

3-Hydroxy-5-(4-phenylphenyl)isoxazole (0.2 g) and 2-(N-tert-butoxycarbonylamino)ethanol (0.15 g) were subjected to reaction and post-treatment in a similar manner to that described in Example 9(a) to obtain the title compound (0.22 g, 69%) as a colorless powder.

Sources & evidence

ORD record
ord-6dbde1ed5b194297b1414ba63db3f45e
Source dataset
uspto-grants-1999_12
Patent number
US06005116

Reaction notes

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