Ethanol → Ethyl 3-(4-isopropylphenyl)prop-2-enoate

HRID 612952Notes

Reaction equation

HRID 612952 reaction equation
[CH:1]([C:4]1[CH:14]=[CH:13][C:7]([CH:8]=[CH:9][C:10]([OH:12])=[O:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].S(=O)(=O)(O)O.[CH2:20](O)[CH3:21]>>[CH2:20]([O:11][C:10](=[O:12])[CH:9]=[CH:8][C:7]1[CH:13]=[CH:14][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=1)[CH3:21]

Participants

4

Reactant 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 728543-(4-(1-Methylethyl)phenyl)-2-propenoic acid

Product 1

HCID 122907Ethyl 3-(4-isopropylphenyl)prop-2-enoateYield 97%

Procedure

4-Isopropylcinnamic acid (5.0 g), conc. sulfuric acid (0.5 ml) and ethanol (50 ml) were subjected to reaction and post-treatment in a similar manner to that described in Reference example 10(a) to obtain the title compound (5.5 g, 97%) as a colorless oil.

Sources & evidence

ORD record
ord-dc07730a5e1242198b578f91d7ac9a64
Source dataset
uspto-grants-1999_12
Patent number
US06005116

Reaction notes

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