Ethanol → Ethyl p-phenoxycinnamate

HRID 612955Notes

Reaction equation

HRID 612955 reaction equation
[O:1]([C:8]1[CH:18]=[CH:17][C:11]([CH:12]=[CH:13][C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(=O)(=O)(O)O.[CH2:24](O)[CH3:25]>>[CH2:24]([O:15][C:14](=[O:16])[CH:13]=[CH:12][C:11]1[CH:17]=[CH:18][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH3:25]

Participants

4

Reactant 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 209923884-Phenoxycinnamic acid

Product 1

HCID 54211320Ethyl p-phenoxycinnamateYield 98%

Procedure

4-Phenoxycinnamic acid (4.0 g), conc. sulfuric acid (0.4 ml) and ethanol (40 ml) were subjected to reaction and post-treatment in a similar manner to that described in Reference example 10(b) to obtain the title compound (4.4 g, 98%) as a colorless oil.

Sources & evidence

ORD record
ord-2aa34445e31d4ce0bfa18c8b7e655c56
Source dataset
uspto-grants-1999_12
Patent number
US06005116

Reaction notes

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